Human antibody screening
After years of practice and experience, Gegen can generate high capacity human natural antibody libraries by using optimized technology including cloning, enzyme digestion , connection, and electrical transformation. Gegen has constructed human Fab antibody library, ScFV antibody library and Semi-synthetic antibody library with a size of 2 x 1011, 5 x1011 and 4 x 1012 respectively. Gegen has also constructed several human specific antigen immunized antibody libraries with a size of 3 x 108 using B cells isolated from particular patients. High affinity human antibodies can be isolated by specific antigen immobilized or antigen containing cells.
贵州福彩网The acquired human antibodies can be whole molecule antibodies (150KD), Fab antibodies (50KD), and ScFv antibodies (25KD).
The antibodies can be binding or blocking antibodies, activating or inhibiting antibodies, conformational epitope or linear epitope antibodies.